Salt of hexamethylenetetramin and process of making same.



f eNrran STATES ADOLF KIRcHER, orsINnLiNeEN, NEAR HUGHST-ON-THE-MAIN, GERMANY, AssIGNoR ro FARBWERKE voRM. MEISTER LUCIUS & BRI'iNING, or nocHsr-oN-rHE-MAIN, GERMANY, A CORPORATION or GERMANY. I

SAIlT OF HEXAJYIIlil'llBZYLENETll'lIEtAlllEllN AND PROCESS OF MAKING SAME.

No Drawing.

'To allwhomitmayconcemf Be it known that I, ADOLF KIBCHER,

Ph. D., chemist, a citizen of the Empire of Germany, residing at V Sindlingen, near Hochst-on-the-Main, ermany, have invented certain new and useful Improvements in a Salt of Hexamethylenetetramin and Process of Making Same, of which the following is a specification.

I have found that a new compound of great therapeutical value is obtained by causing two molecules of hexamethylenetetramin and one molecule of camphoric acid to act upon each other in presence of an indifferent solvent, such, for instance, as methyl-alcohol, chloroform, ethyl-acetate or the like.

The hexamethylenetetramin camphorate thus produced has the formula:

lt is a white body, easilycrystalli zing in alcohol and methyl-alcohol, but is rather diffioultly soluble in chloroform and benzene,

Thenew product is used very successfully in the treatment of cystitis, and it has proved to be a very efiicaciousremedy for curing this disease while its action is not attended.

by any undesirable secondaryeffects such as accompany the use of the hexamethylenetetramin itself. The. administration of the bid by catarrhal afiections.

new product causes an increase of diuresis, rendering alkaline urine acid 1n reactlon and clarlfymg urlne whlch has become tur- Example: 1&0 grams of hexamethylenetetramin and, 100 grams of camphoric acid are dissolved while heating in a sufiicient quantity of chloroform; after cooling, ligroin is added until the mass begins to I Specification of Letters Patent. PatentedJ 111mg 10, 1913. Application filed September 18, 1912. Serial No; 721,027. g

become turbid, whereupon the camphorate is allowed to separate.

Having now described my invention,

what I claim is:

1. The process of preparing a new salt of hexamethylenetetramin, which consists in causing two vmolecules of hexamethylenephoric acid in the presence of an indifi'ere'ntsolvent. g e

T 2. As a new product, thehexamethylene- I tetramin camphorate of the formula:

. 1 Witnesses JEANGRUND, I v. CARL GRUND.

- tetramin to act upon one molecule of -cam- ADOLF KIROHER. f 

